Internet UDP port 5349 is primarily used by the STUN (Session Traversal Utilities for NAT) protocol, which is a standardized set of methods and a network protocol to allow an end host to discover its public Internet Protocol (IP) address if it is located behind a NAT (Network Address Translation). It is also used by TURN (Traversal Using Relays around NAT), a protocol that assists in traversal of network address translators. Examples of software that use this port include WebRTC applications and various VoIP services.
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